Skip to content

Supporting Loved Ones in Addiction | Wed. March 25th

  • Online Recovery
    • Quit Opioids
    • Including prescription pain medication and heroin
    • Suboxone
    • Insurance or self-pay
    • At-home drug screenings
    • Quit Kratom
    • Including 7-OH
    • Medication assistance
    • Insurance or self-pay
    • Whole-person care (anxiety, insomnia, etc.)
    • Quit Drinking
    • Campral
    • Naltrexone
    • Insurance or self-pay
    • 100% Online
    • Non-judgmental providers
    • Help with co-occurring disorders​
    • Recovery groups
    • Real people (No AI bots)
  • About Us
    • Our Research

    Advancing substance use treatment through rigorous, peer-reviewed research and actionable insights.

    • Our Mission

    Everyone deserves access to the gold standard of treatment, without judgment.

    • Growing Our Team

    Join us in transforming addiction treatment and improving lives through digital care.

    • Founded and operated by people in recovery since 2015
  • Resources
    • 33% of members were referred by friends or family
    Free Help Them Heal Guide
    • Articles
    • Member stories
    • Opioid addiction help
    • Suboxone Basics
    • Quit drinking
    • Naltrexone basics
    • For friends and family
    • Workit Health
    • Insurance checker
    • Locations
    • Reviews
    • Resources
    • Mental health apps
    • Helplines and support
    • Community in recovery
    • Medication resources
    • 32k+ App store reviews
    • 35k+ Members
    • 85% of Workit clinicians have supported a loved one
  • Make A Referral
    • Friends and Family

    For friends or family members supporting someone they care about.

    • Partners and Providers

    For healthcare professionals making a patient referral.

    • 33% of members were referred by friends or family
  • Partners
Book now
  • Clinical
  • co-occurring disorders, depression, withdrawal

Does Withdrawal Cause Depression?

  • Fact Checked and Peer Reviewed
  • By Olivia Pennelle

Medication for addiction treatment from home

Discreet, accessible treatment from the privacy of home—
science-backed care is just a click away.

Learn more

What's your goal?

Join the 35k+ members who treated addiction via their phone

A hand holds a Suboxone box up to the camera

A Dangerous Myth: “Suboxone is Just Legal Heroin”

Olivia Pennelle
A young man in a white t-shirt looks at himself in the mirror

Self-Care in Early Recovery

Alaine Sepulveda
Closeup on hands holding a smartphone

Drink Tracking Apps: Can They Help Reduce Your Drinking?

Olivia Pennelle

In this article

Depression commonly goes hand-in-hand with substance use, but how is it connected with withdrawal?

While the decision to quit drinking or using drugs is quite possibly the best decision someone with addiction can make, that doesn’t mean it’s easy. Your life will improve radically. However, you have to first navigate the hurdle of withdrawal. The severity of that withdrawal, and whether you might struggle with depression, really depends on the type of addiction you (or your loved one) were suffering with.

The process of withdrawal

Anyone who has used substances—whether alcohol or drugs—for a prolonged period may go through the process of withdrawal. Why? Over time the body develops a tolerance to the substance, meaning you need more and more to get the same effects. Certain substances, like opioids and benzodiazepines, can cause the body to become physically dependent on them to feel functional. When this occurs, stopping the substance may cause physical symptoms of withdrawal. Withdrawal means that the body is adjusting to no longer having that substance in your system.

The process of withdrawal really depends on the type of substance, how long it has been taken, and in what doses. For example, opioid withdrawal usually begins 8-24 hours after the last dose and can last for 4-10 days. The average physical symptoms of alcohol withdrawal begin 6-36 hours after the last drink and last about 4-5 days. Benzodiazepine withdrawal can start within 1-4 days and last several weeks or months.

As a broad generalization, one can expect to experience physical withdrawal symptoms (which also vary depending on the type of substance) for a period of up to two weeks. Mental and emotional withdrawal symptoms can last longer. In some cases, detoxing from drugs or alcohol can result in post-acute withdrawal syndrome (PAWS), which I’ll discuss more below. It is worth noting that there are medications available that can help alleviate withdrawal symptoms.

Common withdrawal symptoms

Withdrawal symptoms will vary, but broadly speaking, the withdrawal process often includes:

  • Depression
  • Anxiety
  • Restlessness
  • Difficulty sleeping
  • Nausea
  • Diarrhea
  • Sweating
  • Body aches
  • Yawning
  • Mood swings
  • Low energy and fatigue
  • Irritability
  • Runny nose
  • Dilated pupils

As mentioned earlier, the type and severity of withdrawal symptoms depend on the type of substance used, how much was used, and how long it has been used.

Post-acute withdrawal syndrome (PAWS)

In some instances, people in withdrawal may experience symptoms for a prolonged period of time, i.e. beyond the typical two-week window. This extended process of withdrawal is called PAWS. Post-acute withdrawal often happens in bouts of a few days and can recur periodically. So a person doesn’t usually feel PAWS symptoms all the time, non-stop, but in recurring episodes. These episodes can persist for up to a year.

Symptoms of PAWS include:

  • Depression
  • Anxiety
  • Mood swings
  • Low energy/fatigue
  • Chronic pain

While PAWS can happen with any substance withdrawal, it is most common with these substances: alcohol, antipsychotics and antidepressants, benzodiazepines, marijuana, stimulants like cocaine, and opioids.

Not everyone in recovery experiences PAWS, but it is helpful to be aware that it exists. If a person experiences episodes of these symptoms after stopping substance use, it can be a nudge to speak with their medical provider.

Facts about depression

Note that depression was on both the list of common withdrawal symptoms above and on the list of PAWS symptoms. Continued drug use can affect the chemical messaging in the brain associated with motivation and reward. As the brain adjusts to the absence of substances, people may experience symptoms of depression, such as sadness, feelings of hopelessness, lethargy, feeling low or a sense of doom, and lack of energy.

It is important to remember that if you feel like you can’t cope and the depression is prolonged (i.e. longer than the withdrawal period), then you should consult your medical provider. There is treatment for depression, even when it is tied to stopping substance use.

How to navigate depression in withdrawal

It’s important to go into recovery with an awareness of the potential side effects, including depression, so you can plan for them. If you’ve been taking substances for a prolonged period and worry you may experience withdrawal, it’s important that you check in with your medical provider and/or an addiction expert that can support you through the process. You can talk to them about the possibility of medication-assisted treatment that can alleviate withdrawal symptoms. For example, Workit Health clinicians regularly prescribe buprenorphine/naloxone medications like Suboxone to support recovery from opioid use disorder, and can also prescribe comfort medications to ease physical withdrawal symptoms from alcohol and opioids.

While it may seem that depression is overwhelming or too painful to navigate, please remember that there are resources to help you through the process. Once you reach the other side, you will feel relief to live a life in recovery.

Need more help?

You may find the following resources helpful to help navigate withdrawal:

  • SAMHSA National Helpline (website): 1-800-662-HELP (4357) — TTY: 1-800-487-4889
  • Suicide & Crisis Lifeline: 988
  • SAMHSA Treatment Locator for Behavioral Health Treatment Services (website)
  • SAMHSA Disaster Distress Helpline (website): 1-800-985-5990 — Call or text
Does withdrawal cause depression? What can help?

Olivia Pennelle (Liv) has a masters in clinical social work from Portland State University. She is a mental health therapist, writer, and human activist. Her writing has appeared in STAT News, Insider, Filter Magazine, Ravishly, The Temper, and Shondaland. She is the founder of Liv’s Recovery Kitchen, Life After 12-Step Recovery, and Tera Collaborations. She lives near Portland, Oregon. Follow her on Instagram @Livwritesrecovery and @teracollaborations

PrevAlcohol and Night Sweats: Uncomfortable Bedfellows
Suboxone Treatment in Orlando, FloridaNext

Any general advice posted on our blog, website, or app is for informational purposes only and is not intended to replace or substitute for any medical or other advice. Workit Health, Inc. and its affiliated professional entities make no representations or warranties and expressly disclaim any and all liability concerning any treatment, action by, or effect on any person following the general information offered or provided within or through the blog, website, or app. If you have specific concerns or a situation arises in which you require medical advice, you should consult with an appropriately trained and qualified medical services provider.

Top

Get the latest recovery news

Instagram Linkedin-in Facebook-f Youtube
    • Treatments
    • Opioids
    • Kratom
    • Alcohol

 

  • About Workit Health
  • Contact us
  • Our team
  • Media spotlight
  • Careers
  • We Accept Insurance
  • Check insurance
  • Aetna
  • Anthem of Ohio
  • Horizon BCBSNJ
  • Humana
  • Resources
  • What is harm reduction?
  • Addiction recovery resources
  • Suboxone FAQs
  • Blog
  • Friends and Family
  • Resources for friends and family
  • Help Them Heal Guide
  • Refer a loved one
  • Members
  • Login
  • Community
  • Medical records request form
  • Medical Records Fax: 833-923-0584
  • Tech support guides
  • Call us: 855-659-7734 M-F 8am-9pm EST
    • Partners
    • Make a referral
    • For health plans
    • For providers and hospitals
    • Third-party medical records requests
Treatments
    • Opioids
    • Kratom
    • Alcohol
About Us
  • Contact us
  • Our team
  • Media spotlight
  • Careers
Resources
  • What is harm reduction?
  • Addiction recovery resources
  • Suboxone FAQs
  • Blog
Insurance
  • Check insurance
  • Aetna
  • Anthem of Ohio
  • Horizon BCBSNJ
  • Humana
Members
  • Login
  • Community
  • Medical records request form
  • Medical Records Fax: 833-923-0584
  • Tech support guides
  • Call us: 855-659-7734
    M-F 8am-9pm EST
Resources
  • What is harm reduction?
  • Addiction recovery resources
  • Suboxone FAQs
  • Blog
Friends and Family
  • Resources for friends and family
  • Help Them Heal Guide
Partners
    • Make a referral
    • For health plans
    • For providers and hospitals
    • Third-party medical records requests
Locations
  • Arizona
  • California
  • Florida
  • Illinois
  • Michigan
  • Montana
  • New Jersey
  • New Mexico
  • North Carolina
  • Ohio
  • Oklahoma
  • Texas
  • Washington
Read more about Suboxone risks and concerns

Suboxone (buprenorphine/naloxone) is indicated for the treatment of opioid dependence in adults. Suboxone should not be taken by individuals who have been shown to be hypersensitive to buprenorphine or naloxone as serious adverse reactions, including anaphylactic shock, have been reported. Taking Suboxone (buprenorphine/naloxone) with other opioid medicines, benzodiazepines, alcohol, or other central nervous system depressants can cause breathing problems that can lead to coma and death. Other side effects may include headaches, nausea, vomiting, constipation, insomnia, pain, increased sweating, sleepiness, dizziness, coordination problems, physical dependence or abuse, and liver problems. For more information about Suboxone (buprenorphine/naloxone) see Suboxone.com, the full Prescribing Information, and Medication Guide, or talk to your healthcare provider. You are encouraged to report negative side effects of drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

All clinical and medical services are provided by licensed physicians and clinicians who are practicing as employees or contractors of independently owned and operated professional medical practices that are owned by licensed physicians. These medical practices include Workit Health (MI), PLLC; Workit Health (CA), P.C.; Workit Health (NJ), LLC; Workit Health (OH), LLC; Virtual Physician Practice (NY), PLLC; and any other Workit Health professional entity that is established in the future.

Clinic locations

Arizona
2501 N Hayden Rd.
Ste 103
Scottsdale, AZ 85257
fax (HIPAA): (833) 664-5441

California
1460 Maria Lane
Ste 300
Walnut Creek, CA 94596
fax (HIPAA): (855) 716-4494

Florida
600 Heritage Dr.
Ste 210, #17
Jupiter, FL 33458
fax (HIPAA): (813) 200-2822

Illinois
1280 Iroquois Ave
Ste 402
Naperville, IL 60563
fax (HIPAA): (855) 716-4494

Michigan
3300 Washtenaw Ave
Ste 280
Ann Arbor, MI 48104
fax (HIPAA): (855) 716-4494

Montana
415 N Higgins Ave
Ste 6
Missoula, MT 59802
fax (HIPAA): (855) 716-4494

New Jersey
5 Greentree Center
Ste 117
Marlton, NJ 08053
fax (HIPAA): (609) 855-5027

New Mexico
5901 Indian School Road, NE
Ste 212
Albuquerque, NM 87110
fax (HIPAA): (855) 716-4494

North Carolina
3719 Latrobe Drive
Ste 850-M
Charlotte, NC 28211-4827
fax (HIPAA): (855) 716-4494

Ohio
6855 Spring Valley Dr
Ste 110
Holland, OH 43528
fax (HIPAA): (513) 823-3247

Oklahoma
1010 24th Ave NW
Suite 100
Norman, OK 73069
fax (HIPAA): (855) 716-4494

Texas
5373 W Alabama St
Ste 204
Houston, TX 77056
fax (HIPAA): (737) 738-5046

Washington
9116 Gravelly Lake Dr SW
Ste 107 #3, PMB 1963
Lakewood, WA 98499-3148.
fax (HIPAA): (833) 328-1407

AICPA SOC

Terms of Service

Privacy Policy

Notice of Privacy Practice

View Accessibility Statement

© 2026 Workit Health. All rights reserved.

Not ready to start? We'll send you more information:

  • Workit Health

    When I opt in, Workit Health will send information about their program and recovery resources.

    *I agree to receive marketing and member care messages by email. Messaging frequency varies. I can unsubscribe at any time.

    **I agree to receive marketing and member care messages by text (SMS). Messaging frequency varies. Message and data rates may apply. I can opt out at any time by replying STOP. I can reply HELP to receive support. If I do not consent to receive SMS, and Workit Health is unable to reach me by email, I understand that they will not be able to contact me by text.

    Carriers are not liable for delayed or undelivered messages.

    View our Privacy Policy, Terms of Service, and Consent to SMS and Email.

  • Should be Empty:

This site uses cookies to improve your experience. By using this site, you consent to our use of cookies.

Accept Cookies