Manage opioid cravings with naltrexone

Daily naltrexone can help you manage cravings for pain pills or heroin.


Manage opioid cravings with naltrexone

Daily naltrexone can help you manage cravings for pain pills or heroin.

Not sure what to expect from digital naltrexone treatment? Trust our clinical experts to guide you through the process.

Naltrexone is a medication approved by the FDA to treat both alcohol and opioid addiction. We prescribe it in a pill form. In the state of California we are also able to prescribe monthly injections (Vivitrol), to be administered at a local pharmacy.

Naltrexone is an opioid antagonist. It binds to and blocks opioid receptors, which can reduce cravings for opioids like heroin or pain pills. It reduces the euphoric effects of opioid medications like heroin, methadone, and oxycodone. 

Since naltrexone binds to the opioid receptors in your brain, taking it too early can cause precipitated withdrawal and make you feel sick. It’s recommended that you are abstinent from all opioids, including Suboxone, for 7-10 days before beginning naltrexone treatment.

At Workit Health, we find naltrexone works best for people stabilized in recovery, and Suboxone works better for people ready to quit other opioids.

Suboxone and naltrexone are both FDA-approved to treat opioid use disorder, but work differently in the brain. Suboxone, or buprenorphine/naloxone, helps with the withdrawal symptoms caused by opioids and activates opioid receptors in the brain. Naltrexone, rather than activating the receptors, binds to them and blocks them. Because of this, Suboxone can be taken 12-24 hours after other opioids, but naltrexone requires 7-10 days. Each medication may suit different individuals at different stages in recovery, based on their needs and medical history.

No, this is a common misconception, but naltrexone does not reduce your risk of overdose. Naltrexone reduces the euphoric feelings of opioids, which means if you use opioids while taking naltrexone, you may need to use more to feel an effect. In addition to this, because naltrexone binds to the opioid receptors in your brain, it may significantly lower your tolerance. 

Workit Health’s digital opioid use disorder program includes video visits with a clinician, online recovery groups, virtual drug testing, in-app messaging with your care team, and therapeutic courses to help you grow in recovery and meet your goals.

Before your first video appointment* with a clinician, we will have you give us your medical history via the app. After your appointment, medication will be e-prescribed to your local pharmacy.

The right care when you need it most

Effective addiction care isn’t one-size-fits-all. Workit Health provides personalized treatment that is tailored to your own life and goals. Our program brings the gold standard of substance use treatment to the privacy of home. 

Medication-Assisted Treatment
Like any other disease, opioid and alcohol addictions are best treated with medication and online therapy. 

100% Virtual Online Therapy
Our clinicians and therapists help members develop a specialized recovery program based on specific goals and guide group therapy sessions.

Discreet, Affordable, and Evidence-Based
Communicate with our dedicated addiction care team through the safe and secure HIPAA-compliant app.


Questions about our treatment or pricing?

Medication-assisted treatment available in many states

With multiple clinic locations around the country, we are working to bring the very best care to you.

Online coaching available nationwide.

Real people. Real results.

By Workit Health Content Team

Editor Workit Health

Medically Reviewed by Dorothy Moore, N.P.

Updated 11/15/2021


1. Naltrexone. Substance Abuse and Mental Health Services Administration (SAMHSA). Accessed November 2021.

2. Rudolph, K. E., Díaz, I., Luo, S. X., Rotrosen, J., & Nunes, E. V. (2021) Optimizing opioid use disorder treatment with naltrexone or buprenorphine. Drug and Alcohol Dependence, 228: 109031.

3. Medications for Opioid Use Disorder: For Healthcare and Addiction Professionals, Policymakers, Patients, and Families [Internet]. Rockville (MD): Substance Abuse and Mental Health Services Administration (US); 2018. (Treatment Improvement Protocol (TIP) Series, No. 63.) Chapter 3C: Naltrexone. Available from:

4. Morgan, J. R., Schackman, B. R., Weinstein, Z. M., Walley, A. Y., Linas, B. P. (2019) Overdose following initiation of naltrexone and buprenorphine medication treatment for opioid use disorder in a United States commercially insured cohort. Drug and Alcohol Dependence, 200 (34-39).