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  • Quit Opioids
  • Including prescription pain medication and heroin
  • Suboxone
  • Insurance or self-pay
  • At home drug screenings
  • Quit Kratom
  • Including 7-OH
  • Medication assistance
  • Insurance or self-pay
  • Whole-person care (anxiety, insomnia,etc.)
  • Quit Drinking
  • Medication assistance
  • Insurance or self-pay
  • Recovery groups
  • 33% of members are referred by friends or family
Free Help them Heal Guide
  • 100% Online
  • Non-judgmental providers
  • 35k+ Members
  • 3.4k+ Reviews
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Depression and Addiction Recovery

Depression and Addiction​

One-third of people who struggle with addiction also have depression. Treat your dual diagnosis virtually.

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By Workit Health Content Team

Medically Reviewed by Chris Prevette, PA-C

Reviewed: June 21, 2022

Depression is treatable​​

More than 8% of American adults live with depression. Depression is an overwhelming feeling of sadness or loss of interest in day-to-day life that can make you feel hopeless. This mood disorder can have a major impact on quality of life. For some, it affects their appetite, sleeping patterns, ability to work, and relationships. Depression and substance use disorders are common co-occurring disorders. We often refer to this as a dual diagnosis.

Depression is treatable. About 80-90% of people who face depression benefit from treatment and find long-term improvement in their mental health and quality of life.

FAQs: Treating Depression and Addiction

How does alcohol affect depression?

It is common for people to drink in an attempt to escape their mental health disorders. Unfortunately, alcohol can make depression worse even for people who don’t drink heavily. Those who drink to manage their depression are much more likely to develop an alcohol use disorder over time.

Alcohol is classified as a central nervous system depressant, which means it depresses the inhibitory centers of the brain, impedes some neural functions, and slows reaction times. In plain terms, it slows down and blocks certain brain functions. Beyond that, it can also affect the reward system in your brain, making it harder to feel good or even just okay without alcohol, exacerbating depressive symptoms.

How does alcohol affect anxiety?

Alcohol makes anxiety worse. As a depressant, alcohol may initially seem to make a person feel calm and relaxed. But it changes brain chemistry, which can worsen anxiety.

If you experience a great deal of anxiety the day after a heavy drinking episode, this is why. In fact, the Anxiety and Depression Association of America, indicates that around 7 percent of Americans struggle with alcohol-induced anxiety.

Increased anxiety is also a symptom of alcohol withdrawal for those who have alcohol use disorder. Symptoms of alcohol withdrawal also include: sweating, vomiting, nausea, hallucinations, increased heart rate, and even seizures.

Can I drink while taking medication for anxiety?

Using opioids has been linked to subsequent depression, and depression has been associated with longer periods of opioid use.

It is possible for opioid use disorder and depression to create a feedback loop—the presence of one worsens the other. For this reason, it is often best to address depression and opioid use at the same time. Ignoring depression to treat addiction can lead to relapse, and ignoring opioid use disorder to treat depression can prolong mental health struggles.

Can I take medication for depression if I'm taking Suboxone for opioid use disorder?

In most cases, yes. Many antidepressants are well tolerated and effective for those taking Suboxone (buprenorphine/naloxone).

Your doctor needs to be aware of all medications you’re taking in order to make the best recommendations for your care, but you shouldn’t fear that you’ll be forced to choose between treating your opioid use disorder and your co-occurring mental illness.

FDA-approved medications for depression

When clinically appropriate with science-backed therapy creates outstanding results.

SSRIs

Selective serotonin reuptake inhibitors (SSRIs) are the safest and most proven first-line of treatment against depression. They affect brain chemistry and work by increasing serotonin levels in the brain. Many people begin to see a reduction of their symptoms within the first 2 months of treatment. SSRIs are not habit-forming, so they are a good option for many in addiction treatment.

SNRIs

Serotonin and norepinephrine reuptake inhibitors (SNRIs) can be more effective for treating depression in some people. They affect brain chemistry by blocking the reuptake of the neurotransmitters serotonin and norepinephrine in the brain. SNRIs can also sometimes be used to treat other conditions, such as anxiety disorders and chronic pain. Your Workit clinician will help you choose the best medication for you.

Atypical Antidepressants

"Atypical antidepressants" is an umbrella term used for medications that are approved to treat depression that don't fit into other classes of antidepressants. Medications like bupropion, mirtazapine, nefazodone, trazodone, and vortioxetine work differently than SSRIs and SNRIs.

Asking for help is easier than ever

Asking for help for any health condition can be challenging. Depression can make it especially difficult to reach out for support.

Our providers are trained in harm reduction and in the unique needs and concerns of people with substance use disorders and co-occurring mental health issues. They will discuss your situation and medical history with you and prescribe safe medications that fit you best.

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Medically Reviewed

Our pages are medically reviewed and fact-checked by accredited medical professionals to ensure that all statements about medical conditions, symptoms, treatments, procedures and tests, standards of care, and typical protocols are accurate and reflect current guidelines as well as the latest research. However, please remember that the information on this page is for informational purposes only and is not intended to replace or substitute for any medical or other advice. Workit Health, Inc. and its affiliated professional entities make no representations or warranties and expressly disclaim any and all liability concerning any treatment, action by, or effect on any person following the general information offered or provided on this page. If you have specific concerns or a situation arises in which you require medical advice, you should consult with an appropriately trained and qualified medical services provider.

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Read more about Suboxone risks and concerns

Suboxone (buprenorphine/naloxone) is indicated for the treatment of opioid dependence in adults. Suboxone should not be taken by individuals who have been shown to be hypersensitive to buprenorphine or naloxone as serious adverse reactions, including anaphylactic shock, have been reported. Taking Suboxone (buprenorphine/naloxone) with other opioid medicines, benzodiazepines, alcohol, or other central nervous system depressants can cause breathing problems that can lead to coma and death. Other side effects may include headaches, nausea, vomiting, constipation, insomnia, pain, increased sweating, sleepiness, dizziness, coordination problems, physical dependence or abuse, and liver problems. For more information about Suboxone (buprenorphine/naloxone) see Suboxone.com, the full Prescribing Information, and Medication Guide, or talk to your healthcare provider. You are encouraged to report negative side effects of drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

All clinical and medical services are provided by licensed physicians and clinicians who are practicing as employees or contractors of independently owned and operated professional medical practices that are owned by licensed physicians. These medical practices include Workit Health (MI), PLLC; Workit Health (CA), P.C.; Workit Health (NJ), LLC; Workit Health (OH), LLC; Virtual Physician Practice (NY), PLLC; and any other Workit Health professional entity that is established in the future.

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Ste 103
Scottsdale, AZ 85257
fax (HIPAA): (833) 664-5441

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Walnut Creek, CA 94596
fax (HIPAA): (855) 716-4494

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fax (HIPAA): (813) 200-2822

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fax (HIPAA): (855) 716-4494

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Ann Arbor, MI 48104
fax (HIPAA): (855) 716-4494

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Missoula, MT 59802
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Ste 117
Marlton, NJ 08053
fax (HIPAA): (609) 855-5027

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Ste 212
Albuquerque, NM 87110
fax (HIPAA): (855) 716-4494

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Ste 110
Holland, OH 43528
fax (HIPAA): (513) 823-3247

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Norman, OK 73069
fax (HIPAA): (855) 716-4494

Texas
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Ste 204
Houston, TX 77056
fax (HIPAA): (737) 738-5046

Washington
9116 Gravelly Lake Dr SW
Ste 107 #3, PMB 1963
Lakewood, WA 98499-3148.
fax (HIPAA): (833) 328-1407

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